Following a decree by the Persian King Cyrus, conqueror of the Babylonian empire (538 BCE), some 50,000 Jews set out on the First Return to the Land of Israel, led by Zerubabel, a descendant of the House of David. Less than a century later, the Second Return was led by Ezra the Scribe. Over the next four centuries, the Jews knew varying degrees of self-rule under Persian (538-333 BCE) and later Hellenistic (Ptolemaic and Seleucid) overlordship (332-142 BCE).
The repatriation of the Jews under Ezra's inspired leadership, construction of the Second Temple on the site of the First Temple, refortification of Jerusalem's walls and establishment of the Knesset Hagedolah (Great Assembly) as the supreme religious and judicial body of the Jewish people marked the beginning of the Second Jewish Commonwealth (Second Temple period). Within the confines of the Persian Empire, Judah was a nation centered in Jerusalem whose leadership was entrusted to the high priest and council of elders.
As part of the ancient world conquered by Alexander the Great of Greece (332 BCE), the Land remained a Jewish theocracy under Syrian-based Seleucid rulers. When the Jews were prohibited from practicing Judaism and their Temple was desecrated as part of an effort to impose Greek-oriented culture and customs on the entire population, the Jews rose in revolt (166 BCE). First led by Mattathias of the priestly Hasmonean family and then by his son Judah the Maccabee, the Jews subsequently entered Jerusalem and purified the Temple (164 BCE), events commemorated each year by the festival of Hanukkah.
Sources: Israel Ministry of Foreign Affairs